Pages: 1255-1266

Date of Publication: 30-Nov--0001

Pre-analytical Performance in Surgical Pathology: Improvement of the Fixation Technique at Ibn Rochd University Hospital of Casablanca Morocco.

Author: N Anibat, M. Belcaid, A Mellouki, O. Aazzane, A. Rezzaki, M. Keballi, L. Zoubir, N Khlil, M Karkouri

Category: JMSR Pathology

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Abstract:

Background: Pathologists play a crucial role in the management of patients, especially in case of tumor diseases. In order to achieve these missions, adequate course of the pre-analytical phase with all its steps is critical. Fixation is a fundamental part of the pre-analytical process and it is used to protect tissue from decay, making the morphological analysis of tissue and cells possible.

Objective: To improve the fixation process in a central Department of Pathology, serving 4 University hospitals, and to discuss the benefits and drawbacks of each protocol.

Methods: We carried out a prospective study in the Department of Pathology of the Ibn-Rochd University Hospital, Casablanca, Morocco. We evaluated the quality of fixation by buffered formalin compared to unbuffered formalin on surgical breast specimens collected from the Oncology-gynecology Department over a period of 3 months. We evaluated slides reading and current recommendations.

Results __ampersandsign Conclusions: A total of 145 specimens were examined and 5 pathologists participated in this study. Each case was analyzed by two pathologists. We summarized our results in the table 1, below.

Keywords: : Preanalytic, Quality, Fixation Process, Buffered Formalin