<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
      <JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
      <Volume-Issue>Vol. X, n 3</Volume-Issue>
      <Season>March 2024</Season>
      <ArticleType>JMSR Patient Care</ArticleType>
      <ArticleTitle>Profile of Moroccan Patients with Major Lower Limb Amputation: A Review of 296 Cases</ArticleTitle>
          <FirstName>Amine El</FirstName>
      <Abstract>Background: Determine the epidemiological characteristics of patients with major lower limb amputations and compare the results with published data. Methods: A retrospective study was conducted from a chart review of patients with major lower limb amputations over a three-year period from September 2017 to September 2020. Results: 274 patients with 296 major lower limb amputations of which 22 (8%) patients had contralateral limb amputations. 286 (96%) of major lower limb amputations were unilateral and 148 (50%) concerned the right limb. Transtibial and transfemoral amputations were 151 (51%) and 148 (46.6%) respectively. The mean age of the amputated patients was 63 ---PlusMinusSymbol---15 years. The majority of patients were male with a sex ratio of 2.2. 157 (57%) patients are diabetics, 96 (35%) are hypertensive and 84 (30.7%) are active smokers. Diabetes was the main cause of amputation with 56.4%, followed by obliterative arteriopathy of the lower limbs with a percentage of 25.3%. Postoperative complications were observed in 138 (47.4%) patients, of which stump infection represented 41.2%. The average length of hospital stay was 16 days [6, 21]. The in-hospital mortality rate was 6.9% (19 patients). The cause of mortality was mainly due to complications of comorbidity or infection. Conclusion: the major amputation of the lower limb concerned male patients aged 63 ---PlusMinusSymbol--- 15 years who had at least one poorly treated comorbidity. Diabetes and hypertension were the most common comorbidities in our results. Transtibial amputation of the right side was the most frequent due to the complication of diabetic foot.</Abstract>
      <Keywords>Major amputation, Lower limb, Diabetic foot, Infection, Reamputation,Morocco</Keywords>
        <Abstract>https://journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=15126&amp;title=Profile of Moroccan Patients with Major Lower Limb Amputation: A Review of 296 Cases</Abstract>
        <References>Ajibade A, Akinniyi OT, Okoye CS (2013) Indications and complications of major limb amputa- tions in kano, nigeria. ghana Med J 47:4&#13;
	Almaraz MC, Gonzand;aacute;lez-Romero S, Bravo M et al (2012) Incidence of lower limb amputations in individuals with and without diabetes mellitus in Andalusia (Spain) from 1998 to 2006. Diabetes Res Clin Pract 95:399–405. https://doi.org/10.1016/j.diabres.2011.10.035&#13;
	Ambler GK, Thomas-Jones E, Edwards AGK, Twine CP (2020) Prognostic Risk Modelling for Patients Undergoing Major Lower Limb Amputation: An Analysis of the UK National Vascular Registry. Eur J Vasc Endovasc Surg 59:606–613. https://doi.org/10.1016/j.ejvs.2019.12.006&#13;
	Arias Vand;aacute;zquez PI, Castillo Avila RG, Dominguez Zentella M del C et al (2018) Prevalence and correlations between suicide attempt, depression, substance use, and functionality among patients with limb amputations. Int J Rehabil Res 41:52–56. https://doi.org/10.1097/MRR.0000000000000259&#13;
	Chalya PL, Mabula JB, Dass RM et al (2011) Surgical management of Diabetic foot ulcers: A Tanzanian university teaching hospital experience. BMC Res Notes. https://doi.org/10.1186/1756-0500-4-365&#13;
	Chalya PL, Mabula JB, Dass RM et al (2012) Major limb amputations: A tertiary hospital experience in northwestern Tanzania. J Orthop Surg 7:18. https://doi.org/10.1186/1749- 799X-7-18&#13;
	Dutronc H, Gobet A, Dauchy F-A et al (2013) Stump infections after major lower-limb amputation: A 10-year retrospective study. Mand;eacute;decine Mal Infect 43:456–460. https://doi.org/10.1016/j.medmal.2013.09.003&#13;
	Fournet B, Falchetti A, Roques F et al (2020) Epidemiology of the vascular assessment and correlation of the WIfI Classification in lower limb amputee patients at Martinique university hospital in 2018. JMV-J Mand;eacute;decine Vasc 45:114–124. https://doi.org/10.1016/j.jdmv.2020.03.008&#13;
	Icks A, Haastert B, Trautner C et al (2009) Incidence of Lower-limb Amputations in the Diabetic Compared to the Non-diabetic Population. Findings from Nationwide Insurance Data, Germany, 2005–2007. Exp Clin Endocrinol Amp Diabetes 117:500–504. https://doi.org/10.1055/s-0029-1225333&#13;
	Kayssi A, de Mestral C, Forbes TL, Roche-Nagle G (2016) A Canadian population-based description of the indications for lower-extremity amputations and outcomes. 59:9&#13;
	Oliveira Y-S, Iba Ba J, Nsame D et al (2013) Les causes d’amputations des membres infand;eacute;rieurs en rand;eacute;and;eacute;ducation : impact de l’insuffisance artand;eacute;rielle et du diaband;egrave;te. J Rand;eacute;adapt Mand;eacute;dicale Prat Form En Mand;eacute;decine Phys Rand;eacute;adapt 33:122–126. https://doi.org/10.1016/j.jrm.2013.09.003&#13;
	Oliveira YS, Mba Angoue JM, Nguimbi Mbadinga AM et al (2014) Amputation des membres infand;eacute;rieurs et appareillage : expand;eacute;rience du centre de rand;eacute;adaptation et d’appareillage pour handicaps « La Raison de Vivre, Le Droit d’Espand;eacute;rer » and;agrave; Libreville. J Rand;eacute;adapt Mand;eacute;dicale Prat Form En Mand;eacute;decine Phys Rand;eacute;adapt 34:53–59. https://doi.org/10.1016/j.jrm.2014.01.002&#13;
	Ouchemi C, Abdoul T, Dionadji M et al (2016) Les Amputations Majeures Des Membres A L’hopital General De Reference Nationale De N’djamena, Tchad. Eur Sci J ESJ 12:270. https://doi.org/10.19044/esj.2016.v12n12p270&#13;
	Pande SD, Kamal A, Zaw E, Tin AS (2019) Patients following lower limb amputation: A retrospective cohort study showing how to improve survival and rehabilitation outcomes. Int J Surg Open 20:24–28. https://doi.org/10.1016/j.ijso.2019.08.003&#13;
	Sabzi Sarvestani A, Taheri Azam A (2013) Amputation: A Ten-Year Survey. Trauma Mon 18:126–129. https://doi.org/10.5812/traumamon.11693&#13;
	Tobome SR, Hodonou AM, Ay AYD et al (2015) Amputations de membres dans un hand;ocirc;pital de zone du Nord-Band;eacute;nin : and;agrave; propos de 122 cas. :9&#13;
	Zingg M, Nicodeme J-D, Uckay I et al (2014) Amputations du membre infand;eacute;rieur : indications, bilan et complications. Rev Mand;eacute;dicale Suisse 10:2409–13&#13;
	OMS | Journand;eacute;e mondiale du diaband;egrave;te : la moitiand;eacute; des amputations chez les diaband;eacute;tiques pourraient and;ecirc;tre and;eacute;vitand;eacute;s. https://www.who.int/mediacentre/news/releases/2005/pr61/fr/. Zugegriffen: 24. Dezember 2020</References>