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Pages: 1044-1046
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A Rare Cause of Acute Abdomen: Non-Hodgkin’s Lymphoma which Causes Spontaneous Splenic Rupture

Author: Erdal Uysal

Category: JMSR Oncology


Introduction: Non-traumatic spleen rupture is a very rare clinical case. While infectious and traumatic ruptures are so frequent, spontaneous ruptures due to hematological and oncological malignities are very rare. The patients with splenic rupture generally admitted to emergency department because of the acute abdomen. In this case report our aim was to demonstrate that in a patient admitting to the emergency department with acute abdominal findings the typical clinical features of spontaneous splenic rupture caused by a malignant lymphoma. Case Presentation: Sixty two years old Caucasian female patient seek medical advice with the complaint of constantly growing stomach ache on last ten days. There were symptoms of acute abdomen on her physical examination. Contrast-enhanced abdomino-pelvic computed tomography scan has been conducted emergently for the patient. On computed tomography, splenomegali and the findings of ischemia and infarction in an area of 5 cm of the splenic hilus and in widespread perisplenic free fluid were found. Patient urgently underwent a surgery. So, splenectomy was performed due to spontaneous splenic rupture. This patient diagnosed with malign lymphoma on histopathological evaluation. The patient discharged from the hospital due to the recovery, during 4th postoperative day. Conclusion: Non-traumatic splenic ruptures are observed rarely. Spontaneous splenic ruptures due to hematological and oncological diseases are very rare. When making differential diagnosis of acute abdomen, splenic ruptures shall also be in mind. Computed tomography and ultrasonography can be important when making diagnosis. Splenectomy shall be applied emergently during the treatment of spontaneous splenic rupture.

Keywords: Non-Hodgkin’s Lymphoma, acute abdomen, spontaneous, splenic rupture

DOI: 10.46327/msrjg.1.000000000000210



  1. Sugahara K, Togashi H, Aoki M, Mitsuhashi H, Matsuo T, Watanabe H, et al. Spontaneous splenic rupture in a patient with large hepatocellular carcinoma. Am J Gastroenterol 1999; 94:276-8.
  2. Giagounidis AA, Burk M, Meckenstock G, Koch AJ, Schneider W. Pathologic rupture of the spleen in hematologic malignancies: two additional cases. Ann Hematol 1996;73:297-302.
  3. Biswas S, Keddington J, McClanathan J. Large B-cell lymphoma presenting as acute abdominal pain and spontaneous splenic rupture; a case report and review of relevant literature. World J Emerg Surg 2006;1: 35.
  4. Lieberman ME, Levitt A. Spontaneous rupture of the spleen: A case report and literature review. Am J Emerg Med 1989;7:28–31.
  5. Rhee SJ, Sheena Y, Imber C. Spontaneous rupture of the spleen: a rare but important differential of an acute abdomen. Am J Emerg Med 2008;26:733.e5-6.
  6. Klinkert P, Kluit AB, de Vries AC, Puylaert JB. Spontaneous rupture of the spleen: role of ultrasound in diagnosis, treatment, and monitoring. Eur J Surg 1999; 165: 712-3.
  7. Bernat S, García Boyero R, Guinot M, López F, Gozalbo T, Cañigral G. Pathologic rupture of the spleen as the initial manifestation in acute lymphoblastic leukemia. Haematologica 1998; 83: 760-1.