Join us   Log in  


Pages: 660-662
Print Article   Download XML  Download PDF

Colonic Adenomatous Polyposis: Diagnostic Difficulties and Therapeutic Implications in a Surgical Setting in Dakar

Author: Abdourahmane Ndong, Adja Coumba Diallo, Pape Mamadou Faye, Mamadou Ndiaye, Ahmed Diouf, Abdou Niasse, Magatte Faye, Jaafar Aboutalib Thiam, Ibrahima Souleymane Sitor Sarr, Yacine Seye, Mohamed Lamine

Category: JMSR Surgery


Colonic adenomatous polyposis is defined by the presence of more than 100 polyps in the lumen of the colon or rectum. The risk of progression to a colorectal cancer is 100%. The relative rarity of this condition in sub-Saharan Africa explains the problems associated with its management. The aim of this study is to report the diagnostic difficulties and therapeutic implications of colonic adenomatous polyposis at in a surgical setting in Dakar. This is a descriptive retrospective study from January 2012 to December 2015 including patient with colonic adenomatous polyposis confirmed by colonoscopy and histology. In total, 4 patients were included in the study. The mean consultation time was 13.7 years ± 11.8. The mean age was 44.3 years ± 2.8. The sex ratio was 3. Due to their silent symptomatology, colonic adenomatous polyposis is most often found in our context at the stage of complications (metastatic cancer, occlusion, perforation peritonitis). Genetic tests essential for the diagnosis are unavailable in our context. This could explain the relative rarity of this condition in sub-Saharan Africa and the problems associated with its management. Improving the prognosis will necessarily involve the improvement of means both for diagnosis and treatment.

Keywords: Adenoma, Colon, Colonoscopy, Cancer, Polyps, Prophylactic colectomy


Bonnet D. Polypose adénomateuse familiale et oncogénétique. Arch Pédiatrie. 2014;21(5):92–93.

Varesco L. Familial adenomatous polyposis: genetics and epidemiology. Tech Coloproctology. 2004;8(S2):s305?8.

Irabor DO. Emergence of Colorectal Cancer in West Africa: Accepting the Inevitable. Niger Med J J Niger Med Assoc. 2017;58(3):87?91.

Le Mandat A. Chirurgie des polyposes. Arch Pédiatrie. 2014;21(5, Supplement 1):94?5. Bojuwoye MO, Olokoba AB, Ogunlaja OA, Agodirin SO, Ibrahim OK, Okonkwo KC, et al. Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature. Pan Afr Med J . 2018;30.

Alese OB, Irabor DO. Adenomatous polyposis coli in an elderly female Nigerian. Ghana Med J . 2009;43(3).

Peghini M, Barabe P, Seurat P, Philippon G, MORCILLO R, DIALLO A, et al. Les polypes recto-coliques au Sénégal: résultat de 1500 endoscopies basses effectuées à l’hôpital principal de Dakar. Médecine Trop. 1987;47(4):361–364.

Grobbelaar JJ, Wilken E, Ravel TD, Nicholson DL, Kotze MJ. Familial adenomatous polyposis in two Black South African families [Internet]. Clinical Genetics. 2002;61(3):214-217.

Konaté I, Sridi A, Ba PA, Cissé M, Gaye M, Ka I, et al. Étude descriptive des cancers colorectaux à la clinique chirurgicale du CHU Aristide Le Dantec de Dakar. J Afr Cancer Afr J Cancer. 2012;4(4):233?7.

Denis B, Bottlaender J, Weiss AM, Peter A, Breysacher G, Chiappa P, et al. Tous les polypes colorectaux réséqués doivent-ils faire l’objet d’un examen anatomopathologique? Endoscopy. 2009;41(3):CO90.

Smith RA, Andrews KS, Brooks D, Fedewa SA, Manassaram-Baptiste D, Saslow D, et al. Cancer screening in the United States, 2018: A review of current American Cancer Society guidelines and current issues in cancer screening. CA Cancer J Clin. 2018;68(4):297?316.

Mbengue M, Dia D, Diouf ML, Bassene ML, Halim A. Pratique de la coloscopie en Afrique. Analyse de 376 examens à Dakar, Sénégal. Med Afr Noire. 2010;57(11):508.