<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>journal-jmsr</PublisherName> <JournalTitle>Journal of Medical and Surgical Research</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Vol. VI, n 2</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>December 2019</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>JMSR Pathogens</ArticleType> <ArticleTitle>Susceptibility to Tigecycline of Multiresistant Bacteria at Ibn Rochd University Hospital-Casablanca</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>663</FirstPage> <LastPage>666</LastPage> <AuthorList> <Author> <FirstName>Assiya El</FirstName> <LastName>Kettani</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Soufiane</FirstName> <LastName>Arji</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Fakhreddine</FirstName> <LastName>Maaloum</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Khalid</FirstName> <LastName>Katfy</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Khalid</FirstName> <LastName>Zerouali</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Houria</FirstName> <LastName>Belabbes</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Naima</FirstName> <LastName>Elmdaghri</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>A descriptive prospective study was conducted between 2015 and 2017 at the Microbiology laboratory of the Casablanca University Hospital Center to study the Tigecycline susceptibility of isolated multi drug resistant bacteria (MDRB): Imipenem-resistant Acinetobacter baumannii (IRAB), ESBL+/- Carbapenemase -producing enterobacteria (ESBLE), Meticillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococci (VRE). Antibiotic sensitivity tests were performed by diffusion method and those for Tigecycline by E-test strips according to EUCAST / CA-SFM. Breakpoints of interpretation of Tigecycline sensitivity were according to the FDA. A total of 692 MDRB strains were studied. The tigecycline resistance rate was 33.9% (25.3% I, 8.6% R). For IRAB, it was 46% (30.5% I, 15.5% R), for ESBLE 27.9% (100% I), for MRSA 10% (100% R) and no VRE was resistant to Tigecycline. However, as EUCAST has not determined breakpoints for the in vitro thresholds of A.baumannii concerning Tigecycline, conclusions should not be formally established as to its sensibility.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Multi-resistant bacteria, Sensibility, Tigecycline</Keywords> <URLs> <Abstract>https://journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=6730&title=Susceptibility to Tigecycline of Multiresistant Bacteria at Ibn Rochd University Hospital-Casablanca</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>[1] Vergidis PI, Falagas ME. Multidrug-resistant Gram-negative bacterial infections: the emerging threat and potential novel treatment options. Curr Opin Investig Drugs 2008; 9: 176–83 [2] Norskov-Lauritsen N, Marchandin H, Dowzicky MJ. 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