<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>journal-jmsr</PublisherName> <JournalTitle>Journal of Medical and Surgical Research</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Vol. X, n 2</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>December 2023</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>JMSR Pathology</ArticleType> <ArticleTitle>Clinicopathologic Analysis of 169 Cases of Cutaneous Adnexal Tumors in Moroccan Patients: a Retrospective Study.</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1255</FirstPage> <LastPage>1266</LastPage> <AuthorList> <Author> <FirstName>S.</FirstName> <LastName>Moqran</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>L. Tahiri</FirstName> <LastName>Elousrouti</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>S.</FirstName> <LastName>Elloudi</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Fz.</FirstName> <LastName>Elmernissi</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>N.</FirstName> <LastName>Elouatassi</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Mn.</FirstName> <LastName>Elalami</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>L.</FirstName> <LastName>Chbani</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>H.</FirstName> <LastName>El-Fatemi</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>N.</FirstName> <LastName>Hammas</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Background and objectives: Adnexal tumors (ATs) are a heterogeneous entity of primary skin tumors, rarely malignant. Their diagnosis represents a real challenge due to their polymorphism and the locoregional aggressiveness of adnexal carcinomas with their metastatic potential. This study aims to elucidate the morphological and epidemiological characteristics of these tumors through a series of Moroccan patients and to compare them with other series in the literature. Methods: A retrospective study was conducted over a period of 10 years (2013–2022), including all adnexal tumors of skin diagnosed in the Department of Pathology, University hospital Hassan II of Fez, Morocco. The histological study was performed on formalin-fixed and paraffin-embedded tissue sections. The diagnosis was essentially morphological. Special staining or immunohistochemical complement was rarely used. Results: Total number of cases that was diagnosed as ATs were 169. There were 135 benign tumors (80%) and 34 malignant tumors (20%). A female predominance was noted with a sex ratio M/F of 0.72. The mean age was 49 yr (5yr-90yr). Most of the cases were in the age group between the 4th and 5th decades (51–60 yr (32/169 cases)). The head and neck are the most often affected areas (74.6%). About 44% of the tumors displayed sweat gland differentiation, 44% hair follicle differentiation, and 12% of the tumors were sebaceous gland tumors. tumors with follicular differentiation were predominant among adnexal carcinomas (58%). Pilomatricoma (16.6%) was the most prevalent tumor of all ATs, followed by chondroid syringoma (13%). Sebaceous Carcinoma (5.6%) was the most common malignant adnexal tumor. The detailed clinicopathological data are shown in the Table. All of our patients have benefited from a surgical procedure for the treatment of cutaneous adnexal carcinomas. Only 4 patients have been recommended for adjuvant radiotherapy.Following up with our patients allowed us to identify a recurrence in one case in the form of lymph node metastasis and a parotid metastasis in another. Conclusion: Our findings generally concur with those found in the literature, With the exception of the frequency of carcinomas with follicular origin rather than those with sweat gland origin in other series.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Benign, malignant, histopathology, Cutaneous adnexal tumors</Keywords> <URLs> <Abstract>https://journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=14380&title=Clinicopathologic Analysis of 169 Cases of Cutaneous Adnexal Tumors in Moroccan Patients: a Retrospective Study.</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>???</References> </References> </Journal> </Article> </ArticleSet>