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JOURNAL OF MEDICAL AND SURGICAL RESEARCH - Vol. V, n 3, February 2019

Pages: 592-598
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Outcomes of Aortic Valve Replacement in Aortic Stenosis with Impaired Left Ventricular Function: Has the Transvalvular Gradient a Determinant Value in these Results ?

Author: A. Bakkali, S. Lyazidi, R.Sayah, M. Ait Houssa, M. Laaroussi.

Category: JMSR Cardiovascular Disease

Abstract:

Background: Left ventricular dysfunction remains a major prognostic indicator of the outcome of patients undergoing surgery for aortic valve stenosis (AS). These groups of patients are heterogeneous; they include patients with low and high transvalvular gradient. The aim of this study was to compare the results of aortic valve replacement (AVR) for AS and severe left ventri­cular (LV) systolic dysfunction in patients with low and high transvalvular gradient and to identify whether the transvalvular gradient has a determinant value in these results. Methods: In this retrospective bicentric study, 61 patients who underwent isolated AVR for severe AS associated to reduced LV function (LVEF < 40%) were enrolled. The patients were divided into two groups according to the mean transvalvular gradient: Group 1 with mean gradient

Keywords: Severe aortic stenosis, Aortic valve replacement, Low transvalvular gradient, Left ventricular dysfunction, Left ventricular function recovery.

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